BCI Funded Research
Quantification of long term adverse cardiac outcomes in breast cancer survivors treated with and without anthracycline chemotherapy.
Predicting local recurrence in patients treated for ductal carcinoma in situ (DCIS).
Pilot study, to investigate the potential value of microwave radiometry for breast cancer diagnosis and the prediction of prognosis.
Genomic Response Assay
Study to develop an approach for genomic in vitro analysis of fresh tumour samples to assess drug response and inform treatment choice.
Triple Negative Breast Cancer
Comprehensive profiling of clonal dynamics in longitudinal TNBC samples from early disease to metastatic setting.
This grant supports costs associated with clinical research infrastructure at the Edinburgh Breast Unit including a funding for a dedicated research nurse to support all research within the unit.
Validation of a predictive gene expression signature for radiotherapy in breast cancer and study of the underlying mechanisms of resistance for potential therapeutic intent.
Lymph Node Positive Disease
Study to explore the mechanisms underlying differential response to treatment in primary tumours versus nodal metastasis. With the aim of improving prediction of response to treatment.