A randomised control trial of breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer.

Quantification of long term adverse cardiac outcomes in breast cancer survivors treated with and without anthracycline chemotherapy.

Predicting local recurrence in patients treated for ductal carcinoma in situ (DCIS).

Edinburgh Health Economics Info-BC project is looking to discover what matters most to patients when receiving treatment for secondary breast cancer.

Pilot study, to investigate the potential value of microwave radiometry for breast cancer diagnosis and the prediction of prognosis.

Molecular signatures of radiosensitivity and ipsilateral breast tumour recurrence in breast cancer.

Genomics of endocrine therapy resistance: tailoring treatment using personalised genomic analysis in ER-positive breast cancer.

Study to develop an approach for genomic in vitro analysis of fresh tumour samples to assess drug response and inform treatment choice.

Comprehensive profiling of clonal dynamics in longitudinal TNBC samples from early disease to metastatic setting.

Analysing and evaluating the combination effects of Carbonic anhydrase IX (CAIX) inhibition in conjunction with radiotherapy.

A randomized phase III study of radiation doses and fractionation schedules for Ductal Carcinoma in Situ (DCIS) of the breast.

Translational pre-clinical study to investigate novel radio-sensitivity predictive biomarkers in breast cancer.

A natural experiment using Scottish clinical data to estimate the real-world effectiveness of adjuvant chemotherapy in breast cancer patients

This grant supports costs associated with clinical research infrastructure at the Edinburgh Breast Unit including a funding for a dedicated research nurse to support all research within the unit.

Validation of a predictive gene expression signature for radiotherapy in breast cancer and study of the underlying mechanisms of resistance for potential therapeutic intent.

Study to explore the mechanisms underlying differential response to treatment in primary tumours versus nodal metastasis. With the aim of improving prediction of response to treatment.

The role of postmastectomy radiotherapy in intermediate-risk breast cancer (BIG 2.04 MRC SUPREMO trial).

The BCI is funding a 3-year PhD studentship at the University of Edinburgh to explore the genomics underlying the response to treatment in metastatic disease.